Thomas Neylan, MD

Director of the Stress and Health Research Program
Principal Investigator
Psychiatry
+1 415 750-6961

Dr. Neylan is a Professor, In Residence in the Department of Psychiatry at the University of California, San Francisco. He is the Director of the Posttraumatic Stress Disorders (PTSD) Clinic and the Stress and Health Research Program at the San Francisco Veterans Affairs Medical Center. His research has focused on the role of sleep in emotion regulation, cognitive function, and metabolic health, in patients with PTSD, and more recently in aging populations with neurodegenerative disorders. He has been a Principal Investigator on multiple funded projects sponsored by the National Institutes of Health, the National Institute of Justice, the Department of Defense, the Department of Veterans Affairs, and several foundations.

His current funding includes projects examining the role of disturbed sleep on prefrontal executive control and emotion regulation in PTSD, the role of sleep and circadian factors in risk and resilience for developing PTSD in acutely traumatized patients seen in Emergency Departments, a trial examining effects of exercise for PTSD, a human-animal translational study examining the role of maladaptive myelination as a mechanism underpinning the structural and functional brain abnormalities associated with exposure to traumatic stress, and joint clinical and brain bank study of sleep/wake regulation in neurodegenerative tauopathies. Dr. Neylan directs the PTSD Research program at the San Francisco VA Medical Center and is the PI on the PTSD component of the Sierra Pacific Mental Illness Research, Education and Clinical Center which provides infrastructure support to investigators and fellows conducting PTSD research.

Publications: 

Factors associated with high functioning despite distress in post-9/11 veterans.

Rehabilitation psychology

McCaslin SE, Cloitre M, Neylan TC, Garvert DW, Herbst E, Marmar C

Positive impact of IPS supported employment on PTSD-related occupational-psychosocial functional outcomes: Results from a VA randomized-controlled trial.

Psychiatric rehabilitation journal

Mueller L, Wolfe WR, Neylan TC, McCaslin SE, Yehuda R, Flory JD, Kyriakides TC, Toscano R, Davis LL

Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients.

Psychophysiology

Jovanovic T, Duncan EJ, Kaye J, Garza K, Norrholm SD, Inslicht SS, Neylan TC, Mathew SJ, Iosifescu D, Rothbaum BO, Mayberg HS, Dunlop BW

Longitudinal association of PTSD symptoms and self-reported physical functioning among Veterans.

Journal of affective disorders

Ahmadian AJ, Neylan TC, Metzler T, Cohen BE

Factors associated with completing evidence-based psychotherapy for PTSD among veterans in a national healthcare system.

Psychiatry research

Maguen S, Li Y, Madden E, Seal KH, Neylan TC, Patterson OV, DuVall SL, Lujan C, Shiner B

Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers.

Journal of Alzheimer's disease : JAD

La AL, Walsh CM, Neylan TC, Vossel KA, Yaffe K, Krystal AD, Miller BL, Karageorgiou E

Further Exploring the Associations Between Sympathetic Activation, Fear of Sleep, and Insomnia Symptoms in Posttraumatic Stress Disorder.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Kanady JC, Maguen S, Neylan TC

Altered overnight levels of pro-inflammatory cytokines in men and women with posttraumatic stress disorder.

Psychoneuroendocrinology

Küffer A, Straus LD, Prather AA, Inslicht SS, Richards A, Shigenaga JK, Madden E, Metzler TJ, Neylan TC, O'Donovan A

DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder.

Clinical epigenetics

Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB

The role of co-neurotransmitters in sleep and wake regulation.

Molecular psychiatry

Oh J, Petersen C, Walsh CM, Bittencourt JC, Neylan TC, Grinberg LT

Total Sleep Time Interacts With Age to Predict Cognitive Performance Among Adults.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Mohlenhoff BS, Insel PS, Mackin RS, Neylan TC, Flenniken D, Nosheny R, Richards A, Maruff P, Weiner MW

Temporal Stability of Cognitive Functioning and Functional Capacity in Women with Posttraumatic Stress Disorder.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Gould F, Dunlop BW, Rosenthal JB, Iosifescu DV, Mathew SJ, Neylan TC, Rothbaum BO, Nemeroff CB, Harvey PD

Association among anterior cingulate cortex volume, psychophysiological response, and PTSD diagnosis in a Veteran sample.

Neurobiology of learning and memory

Young DA, Chao L, Neylan TC, O'Donovan A, Metzler TJ, Inslicht SS

Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans.

Journal of traumatic stress

Niles AN, Luxenberg A, Neylan TC, Inslicht SS, Richards A, Metzler TJ, Hlavin J, Deng J, O'Donovan A

Cognitive Behavioral Therapy for Insomnia Reduces Fear of Sleep in Individuals With Posttraumatic Stress Disorder.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Kanady JC, Talbot LS, Maguen S, Straus LD, Richards A, Ruoff L, Metzler TJ, Neylan TC

Patterns of Zolpidem Use in Male and Female Veterans Following Revised FDA Dosing Guidelines.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Inslicht SS, Neylan TC

Posttraumatic stress disorder, depression, and suicidal ideation in veterans: Results from the mind your heart study.

Psychiatry research

Arenson MB, Whooley MA, Neylan TC, Maguen S, Metzler TJ, Cohen BE

The interaction of BDNF Val66Met, PTSD, and child abuse on psychophysiological reactivity and HPA axis function in a sample of Gulf War Veterans.

Journal of affective disorders

Young DA, Neylan TC, O'Donovan A, Metzler T, Richards A, Ross JA, Inslicht SS

Deployment Anxiety Reduction Training: A Pilot Study of Acceptability and Feasibility in Current or Recent Active Duty Service Members.

Military medicine

McCaslin SE, Herbst ED, Armitage NH, Allen I, Neylan T, Becket-Davenport C, Choucroun G, Best S, Inslicht SS

Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study.

Journal of neuropathology and experimental neurology

Eser RA, Ehrenberg AJ, Petersen C, Dunlop S, Mejia MB, Suemoto CK, Walsh CM, Rajana H, Oh J, Theofilas P, Seeley WW, Miller BL, Neylan TC, Heinsen H, Grinberg LT

Sleep and hypothalamic pituitary adrenal axis responses to metyrapone in posttraumatic stress disorder.

Psychoneuroendocrinology

Inslicht SS, Rao MN, Richards A, O'Donovan A, Gibson CJ, Baum T, Metzler TJ, Neylan TC

Subjective Sleep Related to Post Traumatic Stress Disorder Symptoms among Trauma-Exposed Men and Women.

Behavioral sleep medicine

Gibson CJ, Richards A, Villanueva C, Barrientos M, Neylan TC, Inslicht SS

Veterans Group Exercise: A randomized pilot trial of an Integrative Exercise program for veterans with posttraumatic stress.

Journal of affective disorders

Goldstein LA, Mehling WE, Metzler TJ, Cohen BE, Barnes DE, Choucroun GJ, Silver A, Talbot LS, Maguen S, Hlavin JA, Chesney MA, Neylan TC

Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy.

Sleep

Walsh CM, Ruoff L, Walker K, Emery A, Varbel J, Karageorgiou E, Luong PN, Mance I, Heuer HW, Boxer AL, Grinberg LT, Kramer JH, Miller BL, Neylan TC

A 12-week integrative exercise program improves self-reported mindfulness and interoceptive awareness in war veterans with posttraumatic stress symptoms.

Journal of clinical psychology

Mehling WE, Chesney MA, Metzler TJ, Goldstein LA, Maguen S, Geronimo C, Agcaoili G, Barnes DE, Hlavin JA, Neylan TC

Reply to: It Is Time to Look for New Treatments for Posttraumatic Stress Disorder: Can Sympathetic System Modulation Be an Answer?

Biological psychiatry

Krystal JH, Davis LL, Neylan TC, Raskind M, Schnurr PP, Stein MB, Vessicchio J, Shiner B, Gleason TC, Huang GD

PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Breen MS, Tylee DS, Maihofer AX, Neylan TC, Mehta D, Binder EB, Chandler SD, Hess JL, Kremen WS, Risbrough VB, Woelk CH, Baker DG, Nievergelt CM, Tsuang MT, Buxbaum JD, Glatt SJ

Suicidality and associated risk factors in outpatients attending a general medical facility in rural Kenya.

Journal of affective disorders

Ongeri L, McCulloch CE, Neylan TC, Bukusi E, Macfarlane SB, Othieno C, Ngugi AK, Meffert SM

Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder.

Biological psychiatry

Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS

Editorial Comment: Predictors of Post-Traumatic Stress Disorder in Acutely Traumatized Older Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Neylan TC

Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary Report.

Alzheimer's & dementia (New York, N. Y.)

Weiner MW, Harvey D, Hayes J, Landau SM, Aisen PS, Petersen RC, Tosun D, Veitch DP, Jack CR, Decarli C, Saykin AJ, Grafman J, Neylanthe TC

It Is Time to Address the Crisis in the Pharmacotherapy of Posttraumatic Stress Disorder: A Consensus Statement of the PTSD Psychopharmacology Working Group.

Biological psychiatry

Krystal JH, Davis LL, Neylan TC, A Raskind M, Schnurr PP, Stein MB, Vessicchio J, Shiner B, Gleason TD, Huang GD

Impact of Killing in War: A Randomized, Controlled Pilot Trial.

Journal of clinical psychology

Maguen S, Burkman K, Madden E, Dinh J, Bosch J, Keyser J, Schmitz M, Neylan TC

Symptom Presentation and Prescription of Sleep Medications for Veterans With Posttraumatic Stress Disorder.

The Journal of nervous and mental disease

Greenbaum MA, Neylan TC, Rosen CS

Brief Report: Sexual Violence Against HIV-Positive Women in the Nyanza Region of Kenya: Is Condom Negotiation an Instigator?

Journal of acquired immune deficiency syndromes (1999)

Onu CC, Dworkin SL, Ongeri LG, Oyaro P, Neylan TC, Cohen CR, Bukusi EA, Rota G, Meffert SM

Sleep and Cognitive Performance From Teens To Old Age: More Is Not Better.

Sleep

Richards A, Inslicht SS, Metzler TJ, Mohlenhoff BS, Rao MN, O'Donovan A, Neylan TC

What I have changed my mind about and why.

European journal of psychotraumatology

Yehuda R, Spiegel D, Southwick S, Davis LL, Neylan TC, Krystal JH

Current posttraumatic stress disorder and exaggerated threat sensitivity associated with elevated inflammation in the Mind Your Heart Study.

Brain, behavior, and immunity

O'Donovan A, Ahmadian AJ, Neylan TC, Pacult MA, Edmondson D, Cohen BE

Observational Evidence for Buprenorphine's Impact on Posttraumatic Stress Symptoms in Veterans With Chronic Pain and Opioid Use Disorder.

The Journal of clinical psychiatry

Seal KH, Maguen S, Bertenthal D, Batki SL, Striebel J, Stein MB, Madden E, Neylan TC

Health impact of human rights testimony: harming the most vulnerable?

BMJ global health

Meffert SM, Shome S, Neylan TC, Musalo K, Fineberg HV, Cooke MM, Volberding PA, Goosby EP

Rest-activity rhythm disruption in progressive supranuclear palsy.

Sleep medicine

Walsh CM, Ruoff L, Varbel J, Walker K, Grinberg LT, Boxer AL, Kramer JH, Miller BL, Neylan TC

Posttraumatic Stress Disorder Is Associated With Worse Endothelial Function Among Veterans.

Journal of the American Heart Association

Grenon SM, Owens CD, Alley H, Perez S, Whooley MA, Neylan TC, Aschbacher K, Gasper WJ, Hilton JF, Cohen BE

Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep.

eNeuro

Schwartz MD, Nguyen AT, Warrier DR, Palmerston JB, Thomas AM, Morairty SR, Neylan TC, Kilduff TS

TRAUMA EXPOSURE AND RISK OF SUICIDAL IDEATION AMONG ETHNICALLY DIVERSE ADULTS.

Depression and anxiety

Beristianos MH, Maguen S, Neylan TC, Byers AL

Trauma Exposure and Risk of Suicidal Ideation Among Older Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Beristianos MH, Maguen S, Neylan TC, Byers AL

Preliminary Evidence of Increased Hippocampal Myelin Content in Veterans with Posttraumatic Stress Disorder.

Frontiers in behavioral neuroscience

Chao LL, Tosun D, Woodward SH, Kaufer D, Neylan TC

Assessing posttraumatic stress related impairment and well-being: The Posttraumatic Stress Related Functioning Inventory (PRFI).

Journal of psychiatric research

McCaslin SE, Maguen S, Metzler T, Bosch J, Neylan TC, Marmar CR

Nature Reviews Disease Primers

Post-traumatic stress disorder

Yehuda R, Hoge CW, McFarlane AC, Vermetten E, Lanius RA, Nievergelt CM, Hobfoll SE, Koenen KC, Neylan TC, Hyman SE

Post-traumatic stress disorder.

Nature reviews. Disease primers

Yehuda R, Hoge CW, McFarlane AC, Vermetten E, Lanius RA, Nievergelt CM, Hobfoll SE, Koenen KC, Neylan TC, Hyman SE

Evidence for disrupted gray matter structural connectivity in posttraumatic stress disorder.

Psychiatry research

Mueller SG, Ng P, Neylan T, Mackin S, Wolkowitz O, Mellon S, Yan X, Flory J, Yehuda R, Marmar CR, Weiner MW

The Dual Hypocretin Receptor Antagonist Almorexant is Permissive for Activation of Wake-Promoting Systems.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Parks GS, Warrier DR, Dittrich L, Schwartz MD, Palmerston JB, Neylan TC, Morairty SR, Kilduff TS

PTSD and obesity in younger and older veterans: Results from the mind your heart study.

Psychiatry research

Smith BN, Tyzik AL, Neylan TC, Cohen BE

Suicide risk in Iraq and Afghanistan veterans with mental health problems in VA care.

Journal of psychiatric research

Maguen S, Madden E, Cohen BE, Bertenthal D, Neylan TC, Seal KH

Metabolic risk factors and posttraumatic stress disorder: the role of sleep in young, healthy adults.

Psychosomatic medicine

Talbot LS, Rao MN, Cohen BE, Richards A, Inslicht SS, O'Donovan A, Maguen S, Metzler TJ, Neylan TC

Subchronic sleep restriction causes tissue-specific insulin resistance.

The Journal of clinical endocrinology and metabolism

Rao MN, Neylan TC, Grunfeld C, Mulligan K, Schambelan M, Schwarz JM

Treating insomnia improves mood state, sleep, and functioning in bipolar disorder: a pilot randomized controlled trial.

Journal of consulting and clinical psychology

Harvey AG, Soehner AM, Kaplan KA, Hein K, Lee J, Kanady J, Li D, Rabe-Hesketh S, Ketter TA, Neylan TC, Buysse DJ

Towards Constructing a New Taxonomy for Psychiatry Using Self-reported Symptoms.

Studies in health technology and informatics

Ross J, Neylan T, Weiner M, Chao L, Samuelson K, Sim I

HIV, violence and women: unmet mental health care needs.

Journal of affective disorders

Zunner B, Dworkin SL, Neylan TC, Bukusi EA, Oyaro P, Cohen CR, Abwok M, Meffert SM

WITHDRAWN: Precuneal and amygdala spontaneous activity and functional connectivity in war-zone-related PTSD.

Psychiatry research

Yan X, Lazar M, Shalev AY, Neylan TC, Wolkowitz OM, Brown AD, Henn-Haase C, Yehuda R, Flory JD, Abu-Amara D, Sodickson DK, Marmar CR

Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain.

Brain structure & function

Vazquez-DeRose J, Schwartz MD, Nguyen AT, Warrier DR, Gulati S, Mathew TK, Neylan TC, Kilduff TS

Altered inflammatory activity associated with reduced hippocampal volume and more severe posttraumatic stress symptoms in Gulf War veterans.

Psychoneuroendocrinology

O'Donovan A, Chao LL, Paulson J, Samuelson KW, Shigenaga JK, Grunfeld C, Weiner MW, Neylan TC

Timing of mental health treatment and PTSD Symptom improvement among Iraq and Afghanistan veterans.

Psychiatric services (Washington, D.C.)

Maguen S, Madden E, Neylan TC, Cohen BE, Bertenthal D, Seal KH

Biomarkers for combat-related PTSD: focus on molecular networks from high-dimensional data.

European journal of psychotraumatology

Neylan TC, Schadt EE, Yehuda R

Topiramate treatment of alcohol use disorder in veterans with posttraumatic stress disorder: a randomized controlled pilot trial.

Alcoholism, clinical and experimental research

Batki SL, Pennington DL, Lasher B, Neylan TC, Metzler T, Waldrop A, Delucchi K, Herbst E

Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder.

Psychoneuroendocrinology

Rao MN, Chau A, Madden E, Inslicht S, Talbot L, Richards A, O'Donovan A, Ruoff L, Grunfeld C, Neylan TC

The mediating effect of sleep quality on the relationship between PTSD and physical activity.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Talbot LS, Neylan TC, Metzler TJ, Cohen BE

Prospective study of police officer spouse/partners: a new pathway to secondary trauma and relationship violence?

PloS one

Meffert SM, Henn-Haase C, Metzler TJ, Qian M, Best S, Hirschfeld A, McCaslin S, Inslicht S, Neylan TC, Marmar CR

Elevated risk for autoimmune disorders in iraq and afghanistan veterans with posttraumatic stress disorder.

Biological psychiatry

O'Donovan A, Cohen BE, Seal KH, Bertenthal D, Margaretten M, Nishimi K, Neylan TC

Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial.

Trials

Dunlop BW, Rothbaum BO, Binder EB, Duncan E, Harvey PD, Jovanovic T, Kelley ME, Kinkead B, Kutner M, Iosifescu DV, Mathew SJ, Neylan TC, Kilts CD, Nemeroff CB, Mayberg HS

Sex differences in neurosteroid and hormonal responses to metyrapone in posttraumatic stress disorder.

Psychopharmacology

Inslicht SS, Richards A, Madden E, Rao MN, O'Donovan A, Talbot LS, Rucker E, Metzler TJ, Hauger RL, Neylan TC

Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress.

Brain, behavior, and immunity

Lindqvist D, Wolkowitz OM, Mellon S, Yehuda R, Flory JD, Henn-Haase C, Bierer LM, Abu-Amara D, Coy M, Neylan TC, Makotkine I, Reus VI, Yan X, Taylor NM, Marmar CR, Dhabhar FS

Are hippocampal size differences in posttraumatic stress disorder mediated by sleep pathology?

Alzheimer's & dementia : the journal of the Alzheimer's Association

Mohlenhoff BS, Chao LL, Buckley ST, Weiner MW, Neylan TC

Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer's disease in veterans, using the Alzheimer's Disease Neuroimaging Initiative.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Weiner MW, Veitch DP, Hayes J, Neylan T, Grafman J, Aisen PS, Petersen RC, Jack C, Jagust W, Trojanowski JQ, Shaw LM, Saykin AJ, Green RC, Harvey D, Toga AW, Friedl KE, Pacifico A, Sheline Y, Yaffe K, Mohlenoff B

Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service.

Journal of psychiatric research

Galatzer-Levy IR, Steenkamp MM, Brown AD, Qian M, Inslicht S, Henn-Haase C, Otte C, Yehuda R, Neylan TC, Marmar CR

Chronicity of posttraumatic stress disorder and risk of disability in older persons.

JAMA psychiatry

Byers AL, Covinsky KE, Neylan TC, Yaffe K

Hippocampal volume is inversely related to PTSD duration.

Psychiatry research

Chao LL, Yaffe K, Samuelson K, Neylan TC

Cognitive behavioral therapy for insomnia in posttraumatic stress disorder: a randomized controlled trial.

Sleep

Talbot LS, Maguen S, Metzler TJ, Schmitz M, McCaslin SE, Richards A, Perlis ML, Posner DA, Weiss B, Ruoff L, Varbel J, Neylan TC

The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats.

Frontiers in neuroscience

Morairty SR, Wilk AJ, Lincoln WU, Neylan TC, Kilduff TS

Posttraumatic stress disorder and cognitive function: findings from the mind your heart study.

The Journal of clinical psychiatry

Cohen BE, Neylan TC, Yaffe K, Samuelson KW, Li Y, Barnes DE

Association between sleep duration and 24-hour urine free cortisol in the MrOS Sleep Study.

PloS one

Rao MN, Blackwell T, Redline S, Punjabi NM, Barrett-Connor E, Neylan TC, Stone KL

Objective evidence of myocardial ischemia in patients with posttraumatic stress disorder.

Biological psychiatry

Turner JH, Neylan TC, Schiller NB, Li Y, Cohen BE

The use of biomarkers in the military: from theory to practice.

Psychoneuroendocrinology

Yehuda R, Neylan TC, Flory JD, McFarlane AC

Posttraumatic stress disorder is associated with emotional eating.

Journal of traumatic stress

Talbot LS, Maguen S, Epel ES, Metzler TJ, Neylan TC

The relationship between body mass index and mental health among Iraq and Afghanistan veterans.

Journal of general internal medicine

Maguen S, Madden E, Cohen B, Bertenthal D, Neylan T, Talbot L, Grunfeld C, Seal K

Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects.

Journal of sleep research

Richards A, Metzler TJ, Ruoff LM, Inslicht SS, Rao M, Talbot LS, Neylan TC

Spontaneous brain activity in combat related PTSD.

Neuroscience letters

Yan X, Brown AD, Lazar M, Cressman VL, Henn-Haase C, Neylan TC, Shalev A, Wolkowitz OM, Hamilton SP, Yehuda R, Sodickson DK, Weiner MW, Marmar CR

Positive and negative emotion prospectively predict trajectories of resilience and distress among high-exposure police officers.

Emotion (Washington, D.C.)

Galatzer-Levy IR, Brown AD, Henn-Haase C, Metzler TJ, Neylan TC, Marmar CR

Exaggerated neurobiological sensitivity to threat as a mechanism linking anxiety with increased risk for diseases of aging.

Neuroscience and biobehavioral reviews

O'Donovan A, Slavich GM, Epel ES, Neylan TC

Sex differences in fear conditioning in posttraumatic stress disorder.

Journal of psychiatric research

Inslicht SS, Metzler TJ, Garcia NM, Pineles SL, Milad MR, Orr SP, Marmar CR, Neylan TC

A randomized trial of stress management for the prevention of new brain lesions in MS.

Neurology

Mohr DC, Lovera J, Brown T, Cohen B, Neylan T, Henry R, Siddique J, Jin L, Daikh D, Pelletier D

Killing in combat may be independently associated with suicidal ideation.

Depression and anxiety

Maguen S, Metzler TJ, Bosch J, Marmar CR, Knight SJ, Neylan TC

Cortisol awakening response prospectively predicts peritraumatic and acute stress reactions in police officers.

Biological psychiatry

Inslicht SS, Otte C, McCaslin SE, Apfel BA, Henn-Haase C, Metzler T, Yehuda R, Neylan TC, Marmar CR

The relationship between Gulf War illness, brain N-acetylaspartate, and post-traumatic stress disorder.

Military medicine

Weiner MW, Meyerhoff DJ, Neylan TC, Hlavin J, Ramage ER, McCoy D, Studholme C, Cardenas V, Marmar C, Truran D, Chu PW, Kornak J, Furlong CE, McCarthy C

Rescuers at risk: a systematic review and meta-regression analysis of the worldwide current prevalence and correlates of PTSD in rescue workers.

Social psychiatry and psychiatric epidemiology

Berger W, Coutinho ES, Figueira I, Marques-Portella C, Luz MP, Neylan TC, Marmar CR, Mendlowicz MV

Changes in brain anatomy during the course of posttraumatic stress disorder.

Psychiatry research

Cardenas VA, Samuelson K, Lenoci M, Studholme C, Neylan TC, Marmar CR, Schuff N, Weiner MW

PTSD criterion A1 events: a literature-based categorization.

Journal of traumatic stress

Luz MP, Mendlowicz M, Marques-Portella C, Gleiser S, Berger W, Neylan TC, Coutinho ES, Figueira I

Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder.

Biological psychiatry

O'Donovan A, Epel E, Lin J, Wolkowitz O, Cohen B, Maguen S, Metzler T, Lenoci M, Blackburn E, Neylan TC

Transcriptional control of monocyte gene expression in post-traumatic stress disorder.

Disease markers

O'Donovan A, Sun B, Cole S, Rempel H, Lenoci M, Pulliam L, Neylan T

Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder.

Journal of psychiatric research

Apfel BA, Otte C, Inslicht SS, McCaslin SE, Henn-Haase C, Metzler TJ, Makotkine I, Yehuda R, Neylan TC, Marmar CR

Suppressed monocyte gene expression profile in men versus women with PTSD.

Brain, behavior, and immunity

Neylan TC, Sun B, Rempel H, Ross J, Lenoci M, O'Donovan A, Pulliam L

Protective factors for posttraumatic stress disorder symptoms in a prospective study of police officers.

Psychiatry research

Yuan C, Wang Z, Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Apfel BA, Tong H, Neylan TC, Fang Y, Marmar CR

Hippocampal volume differences in Gulf War veterans with current versus lifetime posttraumatic stress disorder symptoms.

Biological psychiatry

Apfel BA, Ross J, Hlavin J, Meyerhoff DJ, Metzler TJ, Marmar CR, Weiner MW, Schuff N, Neylan TC

Adaptation effects to sleep studies in participants with and without chronic posttraumatic stress disorder.

Psychophysiology

Herbst E, Metzler TJ, Lenoci M, McCaslin SE, Inslicht S, Marmar CR, Neylan TC

Prior night sleep duration is associated with psychomotor vigilance in a healthy sample of police academy recruits.

Chronobiology international

Neylan TC, Metzler TJ, Henn-Haase C, Blank Y, Tarasovsky G, McCaslin SE, Lenoci M, Marmar CR

Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder.

Progress in neuro-psychopharmacology & biological psychiatry

Berger W, Mehra A, Lenoci M, Metzler TJ, Otte C, Tarasovsky G, Mellon SH, Wolkowitz OM, Marmar CR, Neylan TC

Insomnia severity is associated with a decreased volume of the CA3/dentate gyrus hippocampal subfield.

Biological psychiatry

Neylan TC, Mueller SG, Wang Z, Metzler TJ, Lenoci M, Truran D, Marmar CR, Weiner MW, Schuff N

Posttraumatic stress disorder and risk of dementia among US veterans.

Archives of general psychiatry

Yaffe K, Vittinghoff E, Lindquist K, Barnes D, Covinsky KE, Neylan T, Kluse M, Marmar C

Patterns of altered cortical perfusion and diminished subcortical integrity in posttraumatic stress disorder: an MRI study.

NeuroImage

Schuff N, Zhang Y, Zhan W, Lenoci M, Ching C, Boreta L, Mueller SG, Wang Z, Marmar CR, Weiner MW, Neylan TC

Magnetic resonance imaging of hippocampal subfields in posttraumatic stress disorder.

Archives of general psychiatry

Wang Z, Neylan TC, Mueller SG, Lenoci M, Truran D, Marmar CR, Weiner MW, Schuff N

The DSM-v sleep-wake disorders nosology: an update and an invitation to the sleep community.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Reynolds CF, Redline S

A prospective study of predictors of depression symptoms in police.

Psychiatry research

Wang Z, Inslicht SS, Metzler TJ, Henn-Haase C, McCaslin SE, Tong H, Neylan TC, Marmar CR

Routine work environment stress and PTSD symptoms in police officers.

The Journal of nervous and mental disease

Maguen S, Metzler TJ, McCaslin SE, Inslicht SS, Henn-Haase C, Neylan TC, Marmar CR

Longitudinal effects of PTSD on memory functioning.

Journal of the International Neuropsychological Society : JINS

Samuelson KW, Neylan TC, Lenoci M, Metzler TJ, Cardenas V, Weiner MW, Marmar CR

Family psychiatric history, peritraumatic reactivity, and posttraumatic stress symptoms: a prospective study of police.

Journal of psychiatric research

Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Hart SL, Maguen S, Neylan TC, Marmar CR

Anger expression and sleep quality in patients with coronary heart disease: findings from the Heart and Soul Study.

Psychosomatic medicine

Caska CM, Hendrickson BE, Wong MH, Ali S, Neylan T, Whooley MA

Music and the debate on cerebral dominance: the classic work of Bever and Chiarello.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Trait dissociation predicts posttraumatic stress disorder symptoms in a prospective study of urban police officers.

The Journal of nervous and mental disease

McCaslin SE, Inslicht SS, Metzler TJ, Henn-Haase C, Maguen S, Neylan TC, Choucroun G, Marmar CR

Prospective prediction of posttraumatic stress disorder symptoms using fear potentiated auditory startle responses.

Biological psychiatry

Pole N, Neylan TC, Otte C, Henn-Hasse C, Metzler TJ, Marmar CR

A prospective study of trait anger and PTSD symptoms in police.

Journal of traumatic stress

Meffert SM, Metzler TJ, Henn-Haase C, McCaslin S, Inslicht S, Chemtob C, Neylan T, Marmar CR

Abnormal N-acetylaspartate in hippocampus and anterior cingulate in posttraumatic stress disorder.

Psychiatry research

Schuff N, Neylan TC, Fox-Bosetti S, Lenoci M, Samuelson KW, Studholme C, Kornak J, Marmar CR, Weiner MW

Assessment and treatment for insomnia and fatigue in the symptomatic menopausal woman with psychiatric comorbidity.

Expert review of neurotherapeutics

Alexander JL, Neylan T, Kotz K, Dennerstein L, Richardson G, Rosenbaum R

Role of psychiatric comorbidity on cognitive function during and after the menopausal transition.

Expert review of neurotherapeutics

Alexander JL, Sommer BR, Dennerstein L, Grigorova M, Neylan T, Kotz K, Richardson G, Rosenbaum R

Associations between childhood trauma and emotion-modulated psychophysiological responses to startling sounds: a study of police cadets.

Journal of abnormal psychology

Pole N, Neylan TC, Otte C, Metzler TJ, Best SR, Henn-Haase C, Marmar CR

Effects of metyrapone on hypothalamic-pituitary-adrenal axis and sleep in women with post-traumatic stress disorder.

Biological psychiatry

Otte C, Lenoci M, Metzler T, Yehuda R, Marmar CR, Neylan TC

No improvement of posttraumatic stress disorder symptoms with guanfacine treatment.

The American journal of psychiatry

Neylan TC, Lenoci M, Samuelson KW, Metzler TJ, Henn-Haase C, Hierholzer RW, Lindley SE, Otte C, Schoenfeld FB, Yesavage JA, Marmar CR

Neuropsychological functioning in posttraumatic stress disorder and alcohol abuse.

Neuropsychology

Samuelson KW, Neylan TC, Metzler TJ, Lenoci M, Rothlind J, Henn-Haase C, Choucroun G, Weiner MW, Marmar CR

Distinguishing current from remitted posttraumatic stress disorder.

Archives of general psychiatry

Woodward SH, Neylan TC, Mellman TA, Ross RJ

Association between alexithymia and neuroendocrine response to psychological stress in police academy recruits.

Annals of the New York Academy of Sciences

McCaslin SE, Inslicht SS, Neylan TC, Metzler TJ, Otte C, Lenoci M, Henn-Haase C, Best S, Yehuda R, Marmar CR

Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder.

Annals of the New York Academy of Sciences

Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A

Neuroendocrine regulation of sleep disturbances in PTSD.

Annals of the New York Academy of Sciences

Neylan TC, Otte C, Yehuda R, Marmar CR

Predictors of posttraumatic stress in police and other first responders.

Annals of the New York Academy of Sciences

Marmar CR, McCaslin SE, Metzler TJ, Best S, Weiss DS, Fagan J, Liberman A, Pole N, Otte C, Yehuda R, Mohr D, Neylan T

Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder.

Psychoneuroendocrinology

Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A

Hypothalamic-pituitary-adrenal axis activity and sleep in posttraumatic stress disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Otte C, Lenoci M, Metzler T, Yehuda R, Marmar CR, Neylan TC

PTSD symptoms predict waking salivary cortisol levels in police officers.

Psychoneuroendocrinology

Neylan TC, Brunet A, Pole N, Best SR, Metzler TJ, Yehuda R, Marmar CR

A meta-analysis of cortisol response to challenge in human aging: importance of gender.

Psychoneuroendocrinology

Otte C, Hart S, Neylan TC, Marmar CR, Yaffe K, Mohr DC

Association between childhood trauma and catecholamine response to psychological stress in police academy recruits.

Biological psychiatry

Otte C, Neylan TC, Pole N, Metzler T, Best S, Henn-Haase C, Yehuda R, Marmar CR

Comparisons between high and low peritraumatic dissociators in cardiovascular and emotional activity while remembering trauma.

Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

Pole N, Cumberbatch E, Taylor WM, Metzler TJ, Marmar CR, Neylan TC

Current concepts in pharmacotherapy for posttraumatic stress disorder.

Psychiatric services (Washington, D.C.)

Schoenfeld FB, Marmar CR, Neylan TC

Attention, learning, and memory in posttraumatic stress disorder.

Journal of traumatic stress

Neylan TC, Lenoci M, Rothlind J, Metzler TJ, Schuff N, Du AT, Franklin KW, Weiss DS, Weiner MW, Marmar CR

Applied neuroscience in the study of delirium: the classic work of Engel and Romano.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Cortisol levels are positively correlated with hippocampal N-acetylaspartate.

Biological psychiatry

Neylan TC, Schuff N, Lenoci M, Yehuda R, Weiner MW, Marmar CR

Fear-potentiated startle and posttraumatic stress symptoms in urban police officers.

Journal of traumatic stress

Pole N, Neylan TC, Best SR, Orr SP, Marmar CR

Delta sleep response to metyrapone in post-traumatic stress disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Neylan TC, Lenoci M, Maglione ML, Rosenlicht NZ, Metzler TJ, Otte C, Schoenfeld FB, Yehuda R, Marmar CR

The mediating effects of sleep in the relationship between traumatic stress and health symptoms in urban police officers.

Psychosomatic medicine

Mohr D, Vedantham K, Neylan T, Metzler TJ, Best S, Marmar CR

The effect of nefazodone on subjective and objective sleep quality in posttraumatic stress disorder.

The Journal of clinical psychiatry

Neylan TC, Lenoci M, Maglione ML, Rosenlicht NZ, Leykin Y, Metzler TJ, Schoenfeld FB, Marmar CR

Temporal instability of auditory and visual event-related potentials in posttraumatic stress disorder.

Biological psychiatry

Neylan TC, Jasiukaitis PA, Lenoci M, Scott JC, Metzler TJ, Weiss DS, Schoenfeld FB, Marmar CR

Fiftieth anniversary of the discovery of rapid eye movement (REM) sleep.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Neurodegenerative disorders: George Huntington's description of hereditary chorea.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Comorbidity of bipolar disorder and substance abuse in Costa Rica: pedigree- and population-based studies.

Journal of affective disorders

Escamilla MA, Batki S, Reus VI, Spesny M, Molina J, Service S, Vinogradov S, Neylan T, Mathews C, Meza L, Gallegos A, Montero AP, Cruz ML, Neuhaus J, Roche E, Smith L, Leon P, Freimer NB

Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate.

American journal of human genetics

Ophoff RA, Escamilla MA, Service SK, Spesny M, Meshi DB, Poon W, Molina J, Fournier E, Gallegos A, Mathews C, Neylan T, Batki SL, Roche E, Ramirez M, Silva S, De Mille MC, Dong P, Leon PE, Reus VI, Sandkuijl LA, Freimer NB

Critical incident exposure and sleep quality in police officers.

Psychosomatic medicine

Neylan TC, Metzler TJ, Best SR, Weiss DS, Fagan JA, Liberman A, Rogers C, Vedantham K, Brunet A, Lipsey TL, Marmar CR

New directions in the pharmacotherapy of posttraumatic stress disorder.

The Psychiatric quarterly

Marmar CR, Neylan TC, Schoenfeld FB

Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder.

Biological psychiatry

Schuff N, Neylan TC, Lenoci MA, Du AT, Weiss DS, Marmar CR, Weiner MW

Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.

Proceedings of the National Academy of Sciences of the United States of America

McInnes LA, Service SK, Reus VI, Barnes G, Charlat O, Jawahar S, Lewitzky S, Yang Q, Duong Q, Spesny M, Araya C, Araya X, Gallegos A, Meza L, Molina J, Ramirez R, Mendez R, Silva S, Fournier E, Batki SL, Mathews CA, Neylan T, Glatt CE, Escamilla MA, Luo D, Gajiwala P, Song T, Crook S, Nguyen JB, Roche E, Meyer JM, Leon P, Sandkuijl LA, Freimer NB, Chen H

Cortisol levels predict cognitive impairment induced by electroconvulsive therapy.

Biological psychiatry

Neylan TC, Canick JD, Hall SE, Reus VI, Sapolsky RM, Wolkowitz OM

The Peritraumatic Distress Inventory: a proposed measure of PTSD criterion A2.

The American journal of psychiatry

Brunet A, Weiss DS, Metzler TJ, Best SR, Neylan TC, Rogers C, Fagan J, Marmar CR

Fluvoxamine and sleep disturbances in posttraumatic stress disorder.

Journal of traumatic stress

Neylan TC, Metzler TJ, Schoenfeld FB, Weiss DS, Lenoci M, Best SR, Lipsey TL, Marmar CR

Psychological and physical distress of sheltered battered women.

Health care for women international

Humphreys J, Lee K, Neylan T, Marmar C

Genome screening for linkage disequilibrium in a Costa Rican sample of patients with bipolar-I disorder: a follow-up study on chromosome 18.

American journal of medical genetics

Escamilla MA, McInnes LA, Service SK, Spesny M, Reus VI, Molina J, Gallegos A, Fournier E, Batki S, Neylan T, Matthews C, Vinogradov S, Roche E, Tyler DJ, Shimayoshi N, Mendez R, Ramirez R, Ramirez M, Araya C, Araya X, Leon PE, Sandkuijl LA, Freimer NB

Neurobiological findings in posttraumatic stress disorder: a review.

Dialogues in clinical neuroscience

Vedantham K, Brunet A, Neylan TC, Weiss DS, Mannar CR

Neuropsychiatric consequences of traumatic brain injury: observations from Adolf Meyer.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Sensory gating in chronic posttraumatic stress disorder: reduced auditory P50 suppression in combat veterans.

Biological psychiatry

Neylan TC, Fletcher DJ, Lenoci M, McCallin K, Weiss DS, Schoenfeld FB, Marmar CR, Fein G

Trauma history of sheltered battered women.

Issues in mental health nursing

Humphreys J, Lee K, Neylan T, Marmar C

Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18.

American journal of human genetics

Escamilla MA, McInnes LA, Spesny M, Reus VI, Service SK, Shimayoshi N, Tyler DJ, Silva S, Molina J, Gallegos A, Meza L, Cruz ML, Batki S, Vinogradov S, Neylan T, Nguyen JB, Fournier E, Araya C, Barondes SH, Leon P, Sandkuijl LA, Freimer NB

Frontal lobe function: Mr. Phineas Gage's famous injury.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Sleep patterns of sheltered battered women.

Image--the journal of nursing scholarship

Humphreys JC, Lee KA, Neylan TC, Marmar CR

Sleep disturbances in the Vietnam generation: findings from a nationally representative sample of male Vietnam veterans.

The American journal of psychiatry

Neylan TC, Marmar CR, Metzler TJ, Weiss DS, Zatzick DF, Delucchi KL, Wu RM, Schoenfeld FB

Reduced hippocampal volume and n-acetyl aspartate in posttraumatic stress disorder.

Annals of the New York Academy of Sciences

Schuff N, Marmar CR, Weiss DS, Neylan TC, Schoenfeld F, Fein G, Weiner MW

Brain plasticity: influence of environment.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Open trial of fluvoxamine treatment for combat-related posttraumatic stress disorder.

The Journal of clinical psychiatry

Marmar CR, Schoenfeld F, Weiss DS, Metzler T, Zatzick D, Wu R, Smiga S, Tecott L, Neylan T

Pathophysiology of schizophrenia: dopamine hypothesis.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Physiology of arousal: Moruzzi and Magoun's ascending reticular activating system.

The Journal of neuropsychiatry and clinical neurosciences

Neylan TC

Treatment of sleep disturbances in depressed patients.

The Journal of clinical psychiatry

Neylan TC

CSF levels of diazepam-binding inhibitor correlate with REM latency in schizophrenia, a pilot study.

European archives of psychiatry and clinical neuroscience

van Kammen DP, Guidotti A, Neylan T, Guarneri P, Kelley ME, Gurklis J, Gilbertson MW, Peters JL, Costa E

Delta sleep-inducing-peptide-like immunoreactivity (DSIP-LI) and delta sleep in schizophrenic volunteers.

Sleep

van Kammen DP, Widerlöv E, Neylan TC, Ekman R, Kelley ME, Mouton A, Peters JL

Sleep in schizophrenic patients on and off haloperidol therapy. Clinically stable vs relapsed patients.

Archives of general psychiatry

Neylan TC, van Kammen DP, Kelley ME, Peters JL

CSF chromogranin A-like immunoreactivity in schizophrenia: relationships with REM latency and slow wave sleep.

Psychiatry research

van Kammen DP, O'Connor DT, Neylan TC, Mouton A, Gurklis JA, Gilbertson MW, Peters JL

CSF chromogranin A-like immunoreactivity in schizophrenia. Assessment of clinical and biochemical relationships.

Schizophrenia research

van Kammen DP, Peters J, Yao J, Neylan T, Beuger M, Pontius E, O'Connor DT

Neuropsychiatric symptoms associated with idiopathic calcification of the basal ganglia.

The Journal of nervous and mental disease

Rosenberg DR, Neylan TC, el-Alwar M, Peters J, Van Kammen DP

Sleep disturbance and computerized axial tomographic scan findings in former prisoners of war.

Comprehensive psychiatry

Peters J, van Kammen DP, van Kammen WB, Neylan T

More on ethics of drug discontinuation studies in schizophrenia.

Archives of general psychiatry

Neylan TC, Wright BA, Shelton MD, van Kammen DP

Norepinephrine in acute exacerbations of chronic schizophrenia. Negative symptoms revisited.

Archives of general psychiatry

van Kammen DP, Peters J, Yao J, van Kammen WB, Neylan T, Shaw D, Linnoila M

Biological mechanisms of schizophrenia: an update.

Psychiatric medicine

Neylan TC, van Kammen DP

Decreased slow-wave sleep and enlarged lateral ventricles in schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

van Kammen DP, van Kammen WB, Peters J, Goetz K, Neylan T

Illness beliefs of leprosy patients: use of medical anthropology in clinical practice.

International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association

Neylan TC, Nelson KE, Schauf V, Scollard DM