Sabra Inslicht, PhD

Principal Investigator

+1 415 221-4810 ext. 3341

My research goals include: 1) identifying psychobiological causes and consequences of traumatic stress symptoms; 2) utilizing fear conditioning and extinction models to better understand PTSD; 3) characterizing sex differences in the biology of PTSD; 4) improving measurement techniques in the laboratory and the field such as with mobile health devices; and 5) conducting research that will inform novel interventions for ameliorating prolonged PTSD responses.

Publications:

Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients.

Psychophysiology

Jovanovic T, Duncan EJ, Kaye J, Garza K, Norrholm SD, Inslicht SS, Neylan TC, Mathew SJ, Iosifescu D, Rothbaum BO, Mayberg HS, Dunlop BW

Child abuse interacts with hippocampal and corpus callosum volume on psychophysiological response to startling auditory stimuli in a sample of veterans.

Journal of psychiatric research

Young DA, Neylan TC, Chao LL, O'Donovan A, Metzler TJ, Inslicht SS

Altered overnight levels of pro-inflammatory cytokines in men and women with posttraumatic stress disorder.

Psychoneuroendocrinology

Küffer A, Straus LD, Prather AA, Inslicht SS, Richards A, Shigenaga JK, Madden E, Metzler TJ, Neylan TC, O'Donovan A

Gender Differences in Cardiovascular Risk Related to Diabetes and Posttraumatic Stress Disorder.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Gibson CJ, Li Y, Inslicht SS, Seal KH, Byers AL

Association among anterior cingulate cortex volume, psychophysiological response, and PTSD diagnosis in a Veteran sample.

Neurobiology of learning and memory

Young DA, Chao L, Neylan TC, O'Donovan A, Metzler TJ, Inslicht SS

Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans.

Journal of traumatic stress

Niles AN, Luxenberg A, Neylan TC, Inslicht SS, Richards A, Metzler TJ, Hlavin J, Deng J, O'Donovan A

Patterns of Zolpidem Use in Male and Female Veterans Following Revised FDA Dosing Guidelines.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Inslicht SS, Neylan TC

The interaction of BDNF Val66Met, PTSD, and child abuse on psychophysiological reactivity and HPA axis function in a sample of Gulf War Veterans.

Journal of affective disorders

Young DA, Neylan TC, O'Donovan A, Metzler T, Richards A, Ross JA, Inslicht SS

The effects of early trauma and the FKBP5 gene on PTSD and the HPA axis in a clinical sample of Gulf War veterans.

Psychiatry research

Young DA, Inslicht SS, Metzler TJ, Neylan TC, Ross JA

Deployment Anxiety Reduction Training: A Pilot Study of Acceptability and Feasibility in Current or Recent Active Duty Service Members.

Military medicine

McCaslin SE, Herbst ED, Armitage NH, Allen I, Neylan T, Becket-Davenport C, Choucroun G, Best S, Inslicht SS

Sleep and hypothalamic pituitary adrenal axis responses to metyrapone in posttraumatic stress disorder.

Psychoneuroendocrinology

Inslicht SS, Rao MN, Richards A, O'Donovan A, Gibson CJ, Baum T, Metzler TJ, Neylan TC

Subjective Sleep Related to Post Traumatic Stress Disorder Symptoms among Trauma-Exposed Men and Women.

Behavioral sleep medicine

Gibson CJ, Richards A, Villanueva C, Barrientos M, Neylan TC, Inslicht SS

Repeated Exposure to Experimental Pain Differentiates Combat Traumatic Brain Injury with and without Post-Traumatic Stress Disorder.

Journal of neurotrauma

Strigo IA, Spadoni AD, Inslicht SS, Simmons AN

Assessment of skin conductance in African American and Non-African American participants in studies of conditioned fear.

Psychophysiology

Alexandra Kredlow M, Pineles SL, Inslicht SS, Marin MF, Milad MR, Otto MW, Orr SP

Sleep and Cognitive Performance From Teens To Old Age: More Is Not Better.

Sleep

Richards A, Inslicht SS, Metzler TJ, Mohlenhoff BS, Rao MN, O'Donovan A, Neylan TC

Metabolic risk factors and posttraumatic stress disorder: the role of sleep in young, healthy adults.

Psychosomatic medicine

Talbot LS, Rao MN, Cohen BE, Richards A, Inslicht SS, O'Donovan A, Maguen S, Metzler TJ, Neylan TC

Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder.

Psychoneuroendocrinology

Rao MN, Chau A, Madden E, Inslicht S, Talbot L, Richards A, O'Donovan A, Ruoff L, Grunfeld C, Neylan TC

Prospective study of police officer spouse/partners: a new pathway to secondary trauma and relationship violence?

PloS one

Meffert SM, Henn-Haase C, Metzler TJ, Qian M, Best S, Hirschfeld A, McCaslin S, Inslicht S, Neylan TC, Marmar CR

Sex differences in neurosteroid and hormonal responses to metyrapone in posttraumatic stress disorder.

Psychopharmacology

Inslicht SS, Richards A, Madden E, Rao MN, O'Donovan A, Talbot LS, Rucker E, Metzler TJ, Hauger RL, Neylan TC

Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service.

Journal of psychiatric research

Galatzer-Levy IR, Steenkamp MM, Brown AD, Qian M, Inslicht S, Henn-Haase C, Otte C, Yehuda R, Neylan TC, Marmar CR

Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects.

Journal of sleep research

Richards A, Metzler TJ, Ruoff LM, Inslicht SS, Rao M, Talbot LS, Neylan TC

Sex differences in fear conditioning in posttraumatic stress disorder.

Journal of psychiatric research

Inslicht SS, Metzler TJ, Garcia NM, Pineles SL, Milad MR, Orr SP, Marmar CR, Neylan TC

Cortisol awakening response prospectively predicts peritraumatic and acute stress reactions in police officers.

Biological psychiatry

Inslicht SS, Otte C, McCaslin SE, Apfel BA, Henn-Haase C, Metzler T, Yehuda R, Neylan TC, Marmar CR

Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder.

Journal of psychiatric research

Apfel BA, Otte C, Inslicht SS, McCaslin SE, Henn-Haase C, Metzler TJ, Makotkine I, Yehuda R, Neylan TC, Marmar CR

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Sabra Inslicht, PhD

Stress and Health Research Program