Principal Investigator
M_Psychiatry
+1 415 221-4810 ext. 3341
My research goals include: 1) identifying psychobiological causes and consequences of traumatic stress symptoms; 2) utilizing fear conditioning and extinction models to better understand PTSD; 3) characterizing sex differences in the biology of PTSD; 4) improving measurement techniques in the laboratory and the field such as with mobile health devices; and 5) conducting research that will inform novel interventions for ameliorating prolonged PTSD responses.
Publications
Military Exposures and Early Menopause: Findings From the Gulf War Era Cohort Study (GWECS).
Women's health issues : official publication of the Jacobs Institute of Women's Health
Low anti-Müllerian hormone mediates the association between childhood trauma and PTSD in women but not in men.
Psychoneuroendocrinology
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females.
Brain, behavior, and immunity
Racial and Ethnic Disparities in Reproductive Health Care and Outcomes Among Female Veterans: A Scoping Review.
Health equity
PACAP associated with precise PTSD and fear extinction response in women.
Psychoneuroendocrinology
Gut-Brain Axis: Role of Microbiome, Metabolomics, Hormones, and Stress in Mental Health Disorders.
Cells
An exploratory study on lipidomic profiles in a cohort of individuals with posttraumatic stress disorder.
Scientific reports
Tumor Suppressor MicroRNAs in Clinical and Preclinical Trials for Neurological Disorders.
Pharmaceuticals (Basel, Switzerland)
The lipidome of posttraumatic stress disorder.
bioRxiv : the preprint server for biology
The Middle-Out Approach to reconceptualizing, assessing, and analyzing traumatic stress reactions.
Journal of traumatic stress
Military Sexual Trauma and Menopause Symptoms Among Midlife Women Veterans.
Journal of general internal medicine
Lifetime history of interpersonal partner violence is associated with insomnia among midlife women veterans.
Menopause (New York, N.Y.)
Impact of hormonal contraceptives on sex differences in fear conditioning and fear extinction in PTSD.
Learning & memory (Cold Spring Harbor, N.Y.)
Comparing Heart Rate Analytical Methods to Examine Engagement During Imaginal Prolonged Exposure Therapy: Multicase Study.
American journal of psychotherapy
Veterans Health Administration Screening for Military Sexual Trauma May Miss Over Half of Cases Among Midlife Women Veterans.
Women's health issues : official publication of the Jacobs Institute of Women's Health
Racial/ethnic disparities in the diagnosis and management of menopause symptoms among midlife women veterans.
Menopause (New York, N.Y.)
Chemical set enrichment analysis: Novel insights into sex-specific alterations in primary metabolites in posttraumatic stress and disturbed sleep.
Clinical and translational medicine
Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Ventromedial and insular cortical volume moderates the relationship between BDNF Val66Met and threat sensitivity.
Journal of psychiatric research
COVID-19 related moral injury: Associations with pandemic-related perceived threat and risky and protective behaviors.
Journal of psychiatric research
Examining the Effect of Sleep Disruption on the Neural Correlates of Fear Extinction.
Biological psychiatry. Cognitive neuroscience and neuroimaging
Impulsivity as a multifactorial construct and its relationship to PTSD severity and threat sensitivity.
Psychiatry research
Validation of Sleep Measurement in a Multi-Sensor Consumer Grade Wearable Device in Healthy Young Adults.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
Work by day and sleep by night, do not sleep too little or too much: Effects of sleep duration, time of day and circadian synchrony on flanker-task performance in internet brain-game users from teens to advanced age.
Journal of sleep research
Gender Differences in Threat Biases: Trauma Type Matters in Posttraumatic Stress Disorder.
Journal of traumatic stress
Child abuse interacts with hippocampal and corpus callosum volume on psychophysiological response to startling auditory stimuli in a sample of veterans.
Journal of psychiatric research
Altered overnight levels of pro-inflammatory cytokines in men and women with posttraumatic stress disorder.
Psychoneuroendocrinology
Gender Differences in Cardiovascular Risk Related to Diabetes and Posttraumatic Stress Disorder.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Association among anterior cingulate cortex volume, psychophysiological response, and PTSD diagnosis in a Veteran sample.
Neurobiology of learning and memory
Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans.
Journal of traumatic stress
Patterns of Zolpidem Use in Male and Female Veterans Following Revised FDA Dosing Guidelines.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
The interaction of BDNF Val66Met, PTSD, and child abuse on psychophysiological reactivity and HPA axis function in a sample of Gulf War Veterans.
Journal of affective disorders
The effects of early trauma and the FKBP5 gene on PTSD and the HPA axis in a clinical sample of Gulf War veterans.
Psychiatry research
Deployment Anxiety Reduction Training: A Pilot Study of Acceptability and Feasibility in Current or Recent Active Duty Service Members.
Military medicine
An Open-Label Study of Doxazosin Extended-Release for PTSD: Findings and Recommendations for Future Research on Doxazosin.
Focus (American Psychiatric Publishing)
Subjective Sleep Related to Post Traumatic Stress Disorder Symptoms among Trauma-Exposed Men and Women.
Behavioral sleep medicine
Sleep and hypothalamic pituitary adrenal axis responses to metyrapone in posttraumatic stress disorder.
Psychoneuroendocrinology
Repeated Exposure to Experimental Pain Differentiates Combat Traumatic Brain Injury with and without Post-Traumatic Stress Disorder.
Journal of neurotrauma
Assessment of skin conductance in African American and Non-African American participants in studies of conditioned fear.
Psychophysiology
Metabolic risk factors and posttraumatic stress disorder: the role of sleep in young, healthy adults.
Psychosomatic medicine
Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder.
Psychoneuroendocrinology
Sex differences in neurosteroid and hormonal responses to metyrapone in posttraumatic stress disorder.
Psychopharmacology
Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service.
Journal of psychiatric research
Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects.
Journal of sleep research
Sex differences in fear conditioning in posttraumatic stress disorder.
Journal of psychiatric research
Cortisol awakening response prospectively predicts peritraumatic and acute stress reactions in police officers.
Biological psychiatry
Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder.
Journal of psychiatric research
Protective factors for posttraumatic stress disorder symptoms in a prospective study of police officers.
Psychiatry research
Adaptation effects to sleep studies in participants with and without chronic posttraumatic stress disorder.
Psychophysiology
A prospective study of predictors of depression symptoms in police.
Psychiatry research
Routine work environment stress and PTSD symptoms in police officers.
The Journal of nervous and mental disease
Family psychiatric history, peritraumatic reactivity, and posttraumatic stress symptoms: a prospective study of police.
Journal of psychiatric research
Low expression of catecholamine-O-methyl-transferase gene in obsessive-compulsive disorder.
Journal of anxiety disorders
Trait dissociation predicts posttraumatic stress disorder symptoms in a prospective study of urban police officers.
The Journal of nervous and mental disease
A prospective study of trait anger and PTSD symptoms in police.
Journal of traumatic stress
Association between alexithymia and neuroendocrine response to psychological stress in police academy recruits.
Annals of the New York Academy of Sciences
Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder.
Annals of the New York Academy of Sciences
Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder.
Psychoneuroendocrinology
Posttraumatic stress associated with cancer history and BRCA1/2 genetic testing.
Psychosomatic medicine
Similarity of prior trauma exposure as a determinant of chronic stress responding to an airline disaster.
Journal of consulting and clinical psychology