Nicholas Holder, PhD | Stress and Health Research Program

Assistant Adjunct Professor

M_Psych-VAMC-Admin

Dr. Holder is a clinical psychologist and health systems researcher focused on improving the delivery of trauma-focused evidence-based psychotherapy (TF-EBP) for posttraumatic stress disorder (PTSD). He has developed a program of research focused on informing clinical practice and health systems to improve PTSD treatment, particularly for Veterans receiving care within the Veterans Health Administration. He emphasizes use of real-world electronic health record data and mixed-method designs to both reflect and understand the complexity of delivering effective PTSD treatment. He targets research questions that are likely to have direct, strong clinical implications, particularly related to treatment initiation, engagement, dosing, sequencing, safety, and equity. By applying health services and implementation science methods to PTSD treatment research, his goal is to bridge the gap between treatment efficacy and real-world care delivery

Publications

Is symptom improvement similar during PTSD psychotherapy delivered by video telehealth and in-person in routine veterans health administration care?

Journal of anxiety disorders

Holder N, Batten A, Shiner B, Maguen S

Process Improvement for Engaging With Trauma-Focused Evidence-Based Psychotherapy for PTSD.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS

Holder N, Ranney RM, Purcell N, Iwamasa GY, Delgado AK, Batten A, Neylan TC, Shiner B, Maguen S

A preliminary evaluation of the effectiveness of massed delivery of PTSD psychotherapy in VA residential treatment.

General hospital psychiatry

Holliday R, Holder N, Yamokoski C, Burden J, Sippel LM, Harpaz-Rotem I, Smith NB

Associations between delivery modality and treatment dose and density of trauma-focused evidence-based psychotherapy for posttraumatic stress disorder.

General hospital psychiatry

Holder N, Batten A, Shiner B, Maguen S

Reliable symptom worsening among veterans receiving cognitive processing therapy or prolonged exposure therapy for posttraumatic stress disorder in routine VHA care.

Journal of affective disorders

Holder N, Batten A, Shiner B, Neylan TC, Maguen S

Examining Moral Injury in Legal-Involved Veterans: Psychometric Properties of the Moral Injury Events Scale.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS

Martin WB, Holder N, Holliday R, Jeon-Slaughter H, LePage JP

VA is a Leader in Mental Health and Social Service Research and Operations.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS

Holliday R, Holder N

Transitions to trauma-focused evidence-based psychotherapy for posttraumatic stress disorder from other treatments: a qualitative investigation of clinicians' perspectives.

Cognitive behaviour therapy

Holder N, Ranney RM, Delgado AK, Purcell N, Iwamasa GY, Batten A, Neylan TC, Shiner B, Maguen S

Culturally Considerate Trauma-Focused Post-Traumatic Stress Disorder Treatment in Latine/x Populations: A Scoping Review.

Healthcare (Basel, Switzerland)

Delgado AK, Holliday R, Maguen S, Holder N

Trauma-focused evidence-based psychotherapy for post-traumatic stress disorder delivered via video telehealth in the Veterans Health Administration.

Journal of telemedicine and telecare

Holder N, Batten A, Shiner B, Maguen S

Transitioning into trauma-focused evidence-based psychotherapy for posttraumatic stress disorder from other treatments: a qualitative investigation.

Cognitive behaviour therapy

Holder N, Ranney RM, Delgado AK, Purcell N, Iwamasa GY, Batten A, Neylan TC, Shiner B, Maguen S

Gender as a moderator of associations between military sexual trauma and posttraumatic stress disorder treatment utilization.

Psychological services

Ranney RM, Bernhard PA, Holder N, Vogt D, Blosnich JR, Schneiderman AI, Maguen S

Lower rates of VA service use among Native Hawaiian and Pacific Islander veterans with criminal-legal involvement.

General hospital psychiatry

Holliday R, Holder N, Edwards ER, Wong S, Jordan SE, Stewart K, Stimmel M, Monteith LL

Clinician Concerns About Cognitive Processing Therapy: A Review of the Evidence

Cognitive and Behavioral Practice

LoSavio ST, Holder N, Wells SY, Resick PA

Which veterans with PTSD are most likely to report being told of their diagnosis?

Journal of psychiatric research

Holder N, Ranney RM, Bernhard PA, Holliday R, Vogt D, Hoffmire CA, Blosnich JR, Schneiderman AI, Maguen S

Factors associated with receipt of minimally adequate psychotherapy for PTSD at the Veterans Health Administration.

Journal of psychiatric research

Ranney RM, Bernhard PA, Holder N, Vogt D, Blosnich JR, Schneiderman AI, Maguen S

Advancing health equity by understanding race disparities and other factors associated with PTSD symptom improvement following evidence-based psychotherapy.

Journal of anxiety disorders

Maguen S, Batten A, Hubbard A, Holder N, Burkman K, Cottonham D, Purcell N, Mehlman H, Shiner B

Military sexual trauma among Veterans using and not using VA justice-related programing: A national examination.

Journal of psychiatric research

Holliday R, Holder N, Smith AA, Desai A, Hoffmire CA, Forster JE, Monteith LL

Relationship of social determinants of health with symptom severity among Veterans and non-Veterans with probable posttraumatic stress disorder or depression.

Social psychiatry and psychiatric epidemiology

Holder N, Holliday R, Ranney RM, Bernhard PA, Vogt D, Hoffmire CA, Blosnich JR, Schneiderman AI, Maguen S

Treatment Utilization for Posttraumatic Stress Disorder in a National Sample of Veterans and Nonveterans.

Medical care

Ranney RM, Maguen S, Bernhard PA, Holder N, Vogt D, Blosnich JR, Schneiderman AI

Childhood Sexual Abuse and Military Sexual Trauma Interact to Increase Suicide Risk: Results from a Nationally Representative Veteran Sample.

Journal of interpersonal violence

Holliday R, Nichter B, Holder N, Hill ML, Monteith LL, Norman SB, Pietrzak RH

Institutional Betrayal and Closeness Among Women Veteran Survivors of Military Sexual Trauma: Associations with Self-Directed Violence and Mental Health Symptoms.

Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

Monteith LL, Holder N, Iglesias CD, Holliday R

Association between post-traumatic stress disorder severity and death by suicide in US military veterans: retrospective cohort study.

The British journal of psychiatry : the journal of mental science

Forehand JA, Dufort V, Gradus JL, Maguen S, Watts BV, Jiang T, Holder N, Shiner B

Moral injury and chronic pain in veterans.

Journal of psychiatric research

Ranney RM, Maguen S, Bernhard PA, Holder N, Vogt D, Blosnich JR, Schneiderman AI

The Importance of Context: Using Social Determinants of Health to Improve Research and Treatment of Posttraumatic Stress Disorder

Current treatment options in psychiatry

Holder N, Mehlman H, Delgado AK, Maguen S

Veterans receiving a second course of cognitive processing therapy or prolonged exposure therapy: is it better to switch or stay the same?

Cognitive behaviour therapy

Holder N, Batten AJ, Shiner B, Li Y, Madden E, Neylan TC, Seal KH, Patterson OV, DuVall SL, Maguen S

Psychosocial Outcomes Among Veteran and Non-Veteran Survivors of Sexual Assault.

Journal of interpersonal violence

Holder N, Maguen S, Holliday R, Vogt D, Bernhard PA, Hoffmire CA, Blosnich JR, Schneiderman AI

Treating PTSD in the Context of Concurrent Suicide Risk: Current Evidence and Navigating Complicating Factors

Current treatment options in psychiatry

Holliday, R., Holder, N., Williams, A. M., Monteith, L. L.

Effectiveness and comparative effectiveness of evidence-based psychotherapies for posttraumatic stress disorder in clinical practice.

Psychological medicine

Maguen S, Madden E, Holder N, Li Y, Seal KH, Neylan TC, Lujan C, Patterson OV, DuVall SL, Shiner B

Trends in Medication Prescribing in Patients With PTSD From 2009 to 2018: A National Veterans Administration Study.

The Journal of clinical psychiatry

Holder N, Woods A, Neylan TC, Maguen S, Seal KH, Bernardy N, Wiechers I, Ryder A, Urbieta AM, Cohen BE

Influence of suicidal ideation on mental health care following risk assessment among Iraq and Afghanistan war veterans with posttraumatic stress disorder.

General hospital psychiatry

Holder N, Holliday R, Khan AJ, Shiner B, Neylan TC, Madden E, Li Y, Patterson OV, DuVall SL, Maguen S

Reducing Barriers to Behavioral Treatments for Insomnia: A Qualitative Examination of Veterans' Perspectives of BBTI.

Behavioral sleep medicine

Holder N, Kanady JC, Straus LD, Khan AJ, Purcell N, Huggins J, Gloria R, Neylan TC, Lujan C, Maguen S

A Factor Analysis of the Suicide Cognitions Scale in Veterans with Military Sexual Trauma-Related Posttraumatic Stress Disorder.

Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

Wiblin J, Holder N, Holliday R, Jeon-Slaughter H, LePage J, Surís A

The impact of family bereavement interventions: Qualitative feedback identifies needs

Clinical Practice in Pediatric Psychology

Henning E, Germann JN, Holder N, Nakonezny P, Loftin S, Redondo-Doan B, Jones L, Petty LA, Pratt C, Garza-Saenz M, Isaacs T, Liu K, Winick N

Tailoring manualized treatment to the needs of the client: A review of flexible applications of cognitive processing therapy: Evidence-Based Treatment Methods

Eur J Psychotraumatol

Holder, N., Holliday, R., & Williams, A.

Determining the median effective dose of prolonged exposure therapy for veterans with posttraumatic stress disorder.

Preventing Suicidal Self-Directed Violence Among Survivors of Military Sexual Trauma: Understanding Risk and Applying Evidence-Based Principles

Psychiatr Annals

Holliday, R., Wiblin, J., Holder, N., Gerard, G.R., Matarazzo, B.B., & Monteith, L.L.

How do gender and military sexual trauma impact PTSD symptoms in cognitive processing therapy and prolonged exposure?

Journal of psychiatric research

Khan AJ, Holder N, Li Y, Shiner B, Madden E, Seal K, Neylan TC, Maguen S

Cognitive Processing Therapy for Veterans with Posttraumatic Stress Disorder: What is the Median Effective Dose?

Journal of affective disorders

Holder N, Shiner B, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Maguen S

Factors associated with PTSD symptom improvement among Iraq and Afghanistan veterans receiving evidenced-based psychotherapy.

Journal of affective disorders

Maguen S, Holder N, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Shiner B

Comparing the effectiveness of VA residential PTSD treatment for veterans who do and do not report a history of MST: A national investigation.

Journal of psychiatric research

Holliday R, Smith NB, Holder N, Gross GM, Monteith LL, Maguen S, Hoff RA, Harpaz-Rotem I

Evidence-based psychotherapy trends among posttraumatic stress disorder patients in a national healthcare system, 2001-2014.

Depression and anxiety

Maguen S, Holder N, Madden E, Li Y, Seal KH, Neylan TC, Lujan C, Patterson OV, DuVall SL, Shiner B

Validation of the Timberlawn Couple and Family Evaluation Scales-Self-Report in Veterans with PTSD.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS

Holliday R, Holder N, Wiblin J, Surís A

Timing of evidence-based psychotherapy for posttraumatic stress disorder initiation among Iraq and Afghanistan war veterans in the Veterans Health Administration.

Psychological trauma : theory, research, practice and policy

Holder N, Shiner B, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Maguen S

Treating Posttraumatic Stress Disorder in the Presence of Acute Suicide Risk in Veterans and Active Duty Service Members: A Call for Research.

The Journal of nervous and mental disease

Holliday R, Holder N, Olson-Madden JH, Monteith LL

Predictors of dropout from a randomized clinical trial of cognitive processing therapy for female veterans with military sexual trauma-related PTSD.

Psychiatry research

Holder N, Holliday R, Wiblin J, LePage JP, Surís A

A Preliminary Examination of the Effect of Cognitive Processing Therapy on Sleep Disturbance Among Veterans with Military Sexual Trauma-Related Posttraumatic Stress Disorder.

Traumatology

Holder N, Holliday R, Wiblin J, Surís A

Patterns and temporal precedence of symptom change during cognitive processing therapy for military sexual trauma-related posttraumatic stress disorder.

Behavioural and cognitive psychotherapy

Holder N, Holliday R, Wiblin J, Surís A

Competence in psychology board certification: Unlike a good wine, it does not get better with age

Training and Education in Professional Psychology

Bordes-Edgar, V., Holder, N., Cox, D., Surís, A.

The effect of childhood sexual assault history on outpatient cognitive processing therapy for military sexual trauma-related posttraumatic stress disorder: A preliminary investigation.

Stress and health : journal of the International Society for the Investigation of Stress

Holder N, Holliday R, Surís A

Decreases in Suicide Cognitions After Cognitive Processing Therapy Among Veterans With Posttraumatic Stress Disorder Due to Military Sexual Trauma: A Preliminary Examination.

The Journal of nervous and mental disease

Holliday R, Holder N, Monteith LL, Surís A

Predictors of Unbearability, Unlovability, and Unsolvability in Veterans With Military-Sexual-Trauma-Related Posttraumatic Stress Disorder.

Journal of interpersonal violence

Wiblin J, Holder N, Holliday R, Surís A

A Single-Arm Meta-Analysis of Cognitive Processing Therapy in Addressing Trauma-Related Negative Cognitions

Journal of Aggression, Maltreatment, & Trauma

Holliday, R., Holder, N., & Surís, A.

Reductions in self-blame cognitions predict PTSD improvements with cognitive processing therapy for military sexual trauma-related PTSD.

Psychiatry research

Holliday R, Holder N, Surís A

Childhood Sexual Assault, Quality of Life, and Psychiatric Comorbidity in Veterans With Military and Civilian Sexual Trauma

Military Psychology

Williams, R. C., Holliday, R., Holder, N., Surís, A.

A preliminary examination of the role of psychotherapist fidelity on outcomes of cognitive processing therapy during an RCT for military sexual trauma-related PTSD.

Cognitive behaviour therapy

Holder N, Holliday R, Williams R, Mullen K, Surís A

Role of Borderline Personality Disorder in the Treatment of Military Sexual Trauma-related Posttraumatic Stress Disorder with Cognitive Processing Therapy.

Behavioral medicine (Washington, D.C.)

Holder N, Holliday R, Pai A, Surís A

Therapeutic response to Cognitive Processing Therapy in White and Black female veterans with military sexual trauma-related PTSD.

Cognitive behaviour therapy

Holliday RP, Holder ND, Williamson MLC, Surís A

A Reexamination of Military Sexual Trauma and Posttraumatic Stress Disorder

Psychiatric Annals

Williamson, M. L. C., Holliday, R., Holder, N., North, C. S., Surís, A.

Principles of Mental Health Intervention for Survivors of Major Disasters

Psychiatric Annals

Holder, N., Surís, A., Holliday, R., & North, C. S.

Facilitating Fear-Based Memory Extinction With Dexamethasone: A Randomized Controlled Trial in Male Veterans With Combat-Related PTSD.

Psychiatry

Surís A, Holliday R, Adinoff B, Holder N, North CS

Providers' use of evidence-based treatments for posttraumatic stress disorder: The influence of training, attitudes, and barriers in military and private treatment settings

Best Practices in Mental Health

Borah, E.V., Holder, N., Chen, K.

Psychometric validation of the 16 Item Quick Inventory of Depressive Symptomatology Self-Report Version (QIDS-SR16) in military veterans with PTSD.

Journal of affective disorders

Surís A, Holder N, Holliday R, Clem M